Cristiano Ronaldo will not feature in the Champions League semi-finals for the first time since 2009-10 after Juventus were shocked by Ajax.
Not since Real Madrid suffered a last-16 exit at the hands of Lyon almost a decade ago had Ronaldo missed out on the Champions League's final four.
But Ronaldo's run of eight consecutive semi-finals and three successive titles came to an end courtesy of Ajax's 2-1 second-leg victory over Juventus in Turin on Tuesday.
Ronaldo scored his 126th Champions League goal – and 65th in the knockout stages – to give Juve a 28th-minute lead.
But Ajax, who had beaten Ronaldo's former team Madrid in the last 16, rallied through Donny van de Beek and captain Matthijs de Ligt to claim a memorable 3-2 aggregate victory against the Italian champions.