The Cavaliers have lost another veteran presence on the court.
According to ESPN, Tristan Thompson is expected to miss two to four weeks with a sprained foot.
Thompson is in the midst of a career year with the Cavs as he is averaging 12.0 points and 11.6 rebounds this season.
He has never averaged more than 12 points or double-digit rebounds in a year.
Thompson joins veteran Kevin Love on the injured list.
Love is hoping for a mid-January return from a foot injury of his own.
The Cavs are second to last in the Eastern Conference with a 6-21 record.