Monaco and Aris lost their perfect Basketball Champions League records with defeats to Banvit and CEZ Nymburk respectively on Tuesday.
Only Monaco and Aris boasted 100 per cent records in Group A heading into gameday five, but they came unstuck on the road this time around.
Turkish side Banvit suffered their first loss of the competition at Aris last time out, but responded with an impressive 79-65 victory in a contest which was billed as the game of the week.
Gediminas Orelik led the way with a game-high 25 points, while Gasper Vidmar also shone as Monaco were brought back down to earth.
Howard Sant-Roos poured in 23 points and Diamon Simpson made a telling contribution as CEZ turned on the style to see off Aris 87-79.
Simpson claimed 13 points, four steals and three assists to keep Aris at bay and improve his side's record to 3-2.
Besiktas Sompo Japan march on in Group E, making it five wins out of five with a dramatic 75-74 success against Dinamo Sassari.
Kyle Weems came up with five points in the last 30 seconds as Sassari squandered a 70-59 advantage with four minutes to play to slump to a shattering third defeat.
Proximus Spirou ended their wait for a first win by beating second-placed Partizan 84-70, while Juventus Utena became only the third team to hit 100 points in a Basketball Champions League match in a 104-82 victory over Cibona.
Bakken Bears also claimed a first victory at the expense of Fraport Skyliners, while Ironi Nahariya, Sidigas Avellino, Ironi Nahariya, Stelmet Zielona Gora and ASVEL Lyon-Villeurbanne were also winners.